Job description

Director of Protein Sciences

Director of Protein Sciences

The flexibility of working between Boston and Cairo (working by the pyramids) is a great plus. A brief about Proteinea:

Proteinea, a biotech firm, combines AI, computational biology, and automated biology to innovate in protein discovery and design. As pioneers in the BioTech sector in the MENA region, we focus on creating advanced antibody engineering platforms to improve patient care. Our expertise lies in developing groundbreaking protein design and production technologies, which are reflected in our immunotherapy products.

Our Ankh model stands out globally as an exceptionally efficient protein language model, simultaneously establishing benchmarks in both efficiency and performance.
Proteinea is backed by world-leading investors including Logos Capital, SOS Venture, Shorooq Partners, Sawari Ventures, and TA Ventures, among others.

Job Position Description Responsibilities and Skills

  • - Manage and continue to build the team for recombinant protein expression, purifications, and characterization to support the development of next-generation protein therapies.

  • - Strong understanding and experimental background with demonstrated expertise in recombinant protein expression in E. Coli and mammalian cells.

  • - Ensure the development of robust and high-yielding expression and purification workflows for generating a small library of recombinant proteins for R&D, and preclinical development.

  • - Ensure the development of robust protein purification and characterization workflows on a small and large scale.

  • - Ensure development of pre-formulation and stability assessments of lead development candidates using state-of-the-art biologics characterization and QC methods.

  • - Lead and oversee outsourcing and tech. transfer of protocols and production processes for scale-up and complete characterization to CROs.

  • - Contribute to Proteinea’s research strategy by advancing our portfolio in close collaboration with group leaders in discovery and preclinical research.

  • - Inception and progression of current and future projects up to the identification of novel development candidates and IND.

  • - Provide scientific direction and support to project teams.

  • - Establish and manage external partnerships with CROs, consultants, academic

    collaborators, and other partners.

  • - Supervise and mentor scientists and junior staff members.

    Experience and Qualifications

  • - Ph.D. and/or Post-doctoral training in biochemistry, molecular biology, or related field and a minimum of 8 years of experience in the pharmaceutical/biotechnology industry.

  • - Advanced understanding of R&D, preclinical research, and drug development, as well as the regulatory processes.

  • - Strong working knowledge of recombinant protein expression and characterization with an emphasis on the expression of antibodies; experience with nonstandard biologics formats (ADC, bispecifics etc.) is a plus.

  • - Detailed understanding of recombinant expression, purification, and characterization.

  • - Clear track record of successful discovery and progression of projects from discovery to

    IND is a great plus.

  • - Proven ability to foster scientific excellence and guide strategic decisions in a

    data-driven and solutions-oriented manner.

  • - Proven history of team leadership in an industry setting.

  • - Independence with proven ability to work in a cross-functional and collaborative

    environment.

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