Precision medicine approaches are making steady progress in reaching more patients, but the fundamental problem of identifying driver alterations hiding in plain sight and uncovering novel targeting mechanisms to tap into a vast array of targets remains a significant bottleneck. Our purpose-built, insightful drug discovery platform enables us to find new, overlooked areas of opportunity in the form of high potential targets and design therapeutics for a perfect fit. Our science-driven approach and collective drug discovery expertise guides our overarching drug design strategy. We innovate by leveraging mastery in genomics, computational biophysics, machine learning and chemical biology to look closer at molecular mechanisms selected in tumor evolution to ensure nothing is missed – whether mutations that create novel binding pockets are located at the interface of a broader protein complex, or if they are driving changes in protein conformation – we aim to find them.